Oxidative stress and its effects on reproductive performance in thermally-stressed ewes

This paper reviewed the impact of thermally-induced oxidative stress on reproduction in ewes. Thermally-induced is associated with excess generation reactive oxygen species (ROS) during aerobic respiration and metabolic activities within body. Excess ROS have been implicated pathophysiologic mechanisms impairing reproductive processes, including changes cyclic luteal endometrial poor follicular development, ovulation, fertilisation, embryogenesis, embryonic implantation, placental differentiation foetal growth. High levels pregnancy result disorders such as spontaneous abortions, embryopathies, pre-eclampsia, growth restriction, pre-term abortion low-birth weight. occurs a extreme cold hot temperatures, its animals determined by nature management practices being used farm. Heat suppresses hormonal expression activities, resulting performances, exhibition oestrus behaviour mating ability; while neuroendocrine axis, which adversely affects conception rates behaviours. Other factors exerting negative effects are nutrition, solar radiation, environmental pollutants, high ambient temperature relative humidity, expressed temperature-humidity-index. The stressors contribute to adverse outcomes, increase susceptibility offspring disease compromising immune status overall performance link between processes spermatogenesis, oogenesis, implantation critical therapeutic prophylactic interventions medicine. role state knowledge association outcomes ewes elucidated. It concluded that an important silent condition undermining sheep serious economic loss. Reduction impacts will enhance productivity